Transformation That Lasts.Physician-directed care. Board-certified providers. Medical oversight.
Premier Integrative & Cognitive Institute
Our Vision
To create a world where healing goes deeper than symptom management—where science, compassion, and natural medicine unite to restore clarity, resilience, and purpose.
Our Mission
We are here to help people break free from cycles of pain, trauma, and illness through safe, evidence-based, and integrative care. By blending psychiatry, neuroscience, and natural medicine, we guide patients on a path to real transformation—body, brain, and spirit.
All treatments provided by board certified physicians and licensed medical staff under an integrated neurologic/psychiatric protocol.
What We Do
We provide a multidisciplinary and innovative approach to brain wellness, merging conventional mental health care with pioneering treatments in psychedelics, cellular medicine, and neurology. Our core services include:
Medication Assisted Therapy
Integrative Mental Health
Our mission extends beyond symptom relief — we strive to help each person flourish, integrating cutting-edge science with compassionate, personalized care.
What We Treat
Our treatments support healing, recovery, and transformation across mental health, cognitive health, and whole-body wellness.
Mental Health
Depression, Anxiety,PTSD, OCD, Bipolar Disorder, Traumatic Brain Injury.
Brain Health
Cognitive Assessment, Dementia, Brain Fog, Focus & Performance Issues, Insomnia.
Our Commitment to Safety
Safe. Secure. Supportive.
At our clinic, your safety, privacy, and well-being are our top priorities. All sessions take place in a private, distraction-free environment that fully complies with Colorado’s legal safety protocols and medical standards.
Our Practitioners
Lynn Welch Puana, MD
Founder & Medical Director, Premier Integrative & Cognitive Medical Institute
Lynn Welch Puana, MD is the Founder and Medical Director of the Premier Integrative & Cognitive Medical Institute. After more than two decades treating patients with chronic pain, trauma, addiction, and complex medical needs, she became deeply committed to transforming how we approach brain and mental wellness.
Read More about Lynn
Amir Mahmoud, NP, PMHNP-BC
Clinical Director | Psychiatric-Mental Health Nurse Practitioner
Amir Mahmoud is a board-certified Psychiatric-Mental Health Nurse Practitioner with advanced training in neuroscience-based psychiatry, integrative medicine, and innovative approaches to mental health care. He holds dual bachelor’s degrees in Psychology and Criminal Justice, along with a Master of Science in Nursing and a Master of Business Administration—reflecting both clinical expertise and healthcare leadership.
Read More about AmirEntry Packages for Brain Health & Mental Wellness
From genetics to brainwave activity, we analyze what truly drives your cognition, mood, and long-term brain performance.
Our tiered Brain Health Packages combine advanced genomic testing, clinical-grade brain mapping, and expert medical guidance to create a customized plan for improved clarity, mood balance, and lifelong cognitive resilience.
Silver
Foundational Brain Mapping & Evaluation
- Medical Evaluation
Full medical consultation and goal discussion with provider - Standard Bloodwork
Panel to measure essential biomarkers for a targeted brain and mental wellness plan - Advanced Brain Mapping
EEG and 3D brain imaging that shows brainwave activity and patterns - Treatment Plan
Follow-up visit with provider to review test results and discuss your treatment plan
Gold
Essential Genomics & Brain Mapping for Targeted Mental Wellness Care
- Everything in Silver
All tests and plans included in the foundational entry package - Genomic Testing
Advanced IntellxxDNA® analysis for cognition+memory OR mental wellness - Medical Background Report
Clinician-prepared review and report of your past medical records
Platinum
Our Most Advanced Brain & Mental Wellness Evaluation
- Everything in Silver & Gold
All tests, plans, and reports included in the foundational and essential packages - Genomic Testing
Advanced IntellxxDNA® analysis for BOTH cognition+memory AND mental wellness
Frequently Asked Questions
- Are psychedelic therapies safe and legal?Yes. Ketamine is FDA-approved and administered under medical supervision. Psilocybin services are regulated in Colorado and may be available in licensed or approved settings. Availability depends on state regulations and practitioner credentials.
- How do ketamine and psilocybin treatments work?They activate neuroplasticity, helping the brain rewire itself while easing symptoms of depression, PTSD, and trauma.
- What's included in my first visit?A comprehensive evaluation, personalized treatment plan, and guidance on the best next steps.
- How do peptides and regenerative therapies support mental health?By improving cellular repair, balancing hormones, and reducing inflammation, peptides enhance both physical and emotional resilience.
- Do you offer both in-person and virtual care?Yes — we provide online mental health services throughout Colorado, with select therapies (ketamine, neurocognitive biofeedback, IV, red light) available in-person.
- Do you accept insurance?We’re not an insurance-based practice due to the depth and complexity of the care we provide, which extends beyond what insurance typically covers. Traditional insurance rewards short visits, high patient volume, and limited, code-based treatment plans, while we prioritize time, depth, and clinically driven decisions. Many of our offerings — including functional brain mapping, quantitative EEG analysis, precision cognitive and mental-health programs, integrative protocols, peptide and cellular optimization therapies, psychedelic-adjacent preparation and integration, extended visits, and high-touch follow-up — are not covered by insurance. This approach allows us to deliver comprehensive, root-cause care without the constraints of the traditional insurance model.
Limited Time Promotion
For a limited time, get a comprehensive EEG brain scan for $49. This safe, non-invasive assessment provides insight into brain function, with results reviewed by trained professionals. Appointments are limited—get on the waiting list today.